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Generic Aciphex (Rabeprazole)
Aciphex reduces amount of acid in the stomach and relieves symptoms of gastroesophageal reflux disease.
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30pills
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10mg
60pills
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10mg
90pills
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10mg
120pills
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10mg
180pills
Aciphex $136.00
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10mg
360pills
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$203.99
$0.57 per pill
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20mg
10pills
Aciphex $23.00
$18.99
$1.90 per pill
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20mg
30pills
Aciphex $58.00
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20mg
60pills
Aciphex $103.00
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20mg
90pills
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20mg
120pills
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20mg
180pills
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20mg
360pills
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Aciphex - the answer

About About Drugs. Aciphex is the brand name of the drug rabeprazole, which is used for the treatment of gastroesophageal reflux disease Acipheexa chronic digestive disorder. Monitor digoxin concentrations. With ACIPHEX Aciphex mg and 40 mg Acjphex day, significant effects on gastric and esophageal pH were noted after one day of treatment, and more pronounced after seven days of treatment. Do not take Acuphex doses at one time. If you are Acphex consumer Afiphex patient please visit this version. A pre- and postnatal developmental toxicity study in rats with additional endpoints to evaluate bone development was performed with a different PPI at about 3. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. See also: Aciphex drug interactions in more detail. No formal drug interaction studies of methotrexate with PPIs have been conducted [see Warnings and Precautions 5. Serious side effects have been reported with Aciphex including the following: serious allergic reactions. The above synthesis pathway begins with 2,3-dimethypyridine N -oxide 1. Decreased exposure of some antiretroviral drugs e. Rare reports of cyanocobalamin deficiency occurring with acid-suppressing therapy have been reported in the literature. AcipHex is for short-term use only, usually 4 to 8 weeks. Rabeprazole is classified as a substituted benzimidazolelike omeprazolelansoprazoleand pantoprazole. The structural formula is:. Four cases of acute interstitial nephritis associated with Aciphex reported in Canada. You should take your next dose at your regular time. ACIPHEX also prevented recurrence of gastric hypersecretion and manifestations of acid-peptic disease in all patients. Rabeprazole comes as a delayed-release releases the medication in the intestine to prevent break-down of the medication by stomach acids tablet and a delayed-release sprinkle capsule capsule that contains small granules of medication that are sprinkled on food or liquid to take by mouth. See the prescribing information for other drugs dependent on gastric pH for absorption. Potentially increased exposure of tacrolimus, especially in transplant patients who are intermediate or poor metabolizers of CYP2C Generally, histological findings were observed without organ involvement. Rabeprazole is extensively protein bound and is not readily dialyzable. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. In a group of subjects treated with 20 mg ACIPHEX delayed-release tablets for 4 weeks a doubling of mean serum gastrin concentrations was observed. Other uses for this medicine. In a multicenter, open-label study of adolescent patients 12 to 16 years of age with a clinical diagnosis of symptomatic GERD or endoscopically proven GERD, the adverse event profile was similar to that of adults. An international randomized, double-blind, active-controlled trial was conducted in patients comparing 20 mg ACIPHEX delayed-release tablets once daily with 20 mg omeprazole once daily. Tell your doctor right away if you have any of these symptoms: seizures dizziness abnormal or fast heart beat jitteriness jerking movements or shaking tremors muscle weakness spasms of the hands and feet cramps or muscle aches spasm of the voice box Your doctor may check the level of magnesium in your body before you start taking Aciphex, during treatment, or if you will be taking Aciphex for a long period of time. Back Next. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach. People who are taking multiple daily doses of proton pump inhibitor medicines for a long period of time may have an increased risk of fractures of the hip, wrist, or spine. Take Aciphex for as Aciphex as it is prescribed even Acpihex you feel better. Stomach acid can damage erode the lining Aciphxe your esophagus. Rabeprazole can Acipnex the results of certain medical tests. When studied in vitro, rabeprazole is chemically activated at pH 1. Drug Status Rx. Patients with H. Store it at room temperature and away from excess heat and moisture not in the bathroom. Enter section text here Pharmacokinetic parameters in adolescent patients with GERD 12 to 16 years of age were within the range observed in healthy adult subjects. Enter section text here 8. Aciphex and Lactation Back to Top. This includes a condition called Zollinger-Ellison syndrome. ACIPHEX is contraindicated in patients with known hypersensitivity to rabeprazole, substituted benzimidazoles, or to any component of the formulation. This Medication Guide has been approved by the U. Aciphex dosage information in more detail. Some conditions are treated with a combination of rabeprazole and antibiotics. What should I know about storage and disposal of this medication? Whether or not interactions of rabeprazole sodium with other drugs metabolized by CYP2C19 would be different between extensive metabolizers and poor metabolizers has not been studied. Combined Administration with Antimicrobials : Sixteen healthy volunteers genotyped as extensive metabolizers with respect to CYP2C19 were given 20 mg rabeprazole sodium, mg amoxicillin, mg clarithromycin, or all 3 drugs in a four-way crossover study. Rabeprazole was negative in the in vitro Chinese hamster Aciphex cell chromosome aberration test, the in vivo mouse micronucleus test, and the in vivo and ex vivo rat hepatocyte unscheduled DNA synthesis UDS tests. Independent risk factors for pneumonia included age, male gender, underlying cerebrovascular disease, chronic pulmonary disease, congestive heart failure, diabetes mellitus, and antipsychotic use. Your Personal Message. I have gone to the doctor's office twice and they said I had the flu but I know I did not. Several published observational studies in adults suggest that PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine. Upon reading a book on HHC, I came across information that stated I should not be taking a proton pump inhibitor. Keep this medication in the container it came in, tightly closed, and out of reach of children. You may or may not have a fever. Food and Drug Administration. Tell your doctor if you are urinating less than usual, or if you have blood in your urine. If you are a consumer or patient please visit this version. Rabeprazole is present in rat milk. However, the background risk in the U. Tell your doctor if you are urinating less than usual, or if you have blood in your urine. Rabeprazole may cause other side effects. Clostridium difficile -Associated Diarrhea. This medication works by disabling the acid producing pumps in the stomach that contribute to the increased amount of acid in conditions like acid reflux. Do not stop or change the amount Aciphex medication you take without talking to your doctor first. Expert Opinion on Drug Safety. If you are a consumer or patient please visit this version. Its demethylated-metabolite was also positive in the Ames test. Your doctor may check the level of magnesium in your body before you start taking Aciphex, during treatment, or if you will be taking Aciphex for a long period of time. Doses should be adjusted to individual patient needs and should continue for as long as clinically indicated. Saponification followed by treatment with thionyl chloride then Aciphex the primary alcohol Acilhex. Two U. After opening the capsule, you sprinkle the drug contents onto a spoonful of Aci;hex food, such as applesauce, or a liquid. Serious side effects have been reported with Aciphex including the following: serious allergic reactions. Rabeprazole is contraindicated in patients with known hypersensitivity to rabeprazole, substituted benzimidazoles or to any component of the formulation. While this theoretically translates into a faster onset of action for rabeprazole's acid-inhibiting effect, the clinical implications of this fact have yet to be elucidated. DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. In the event of overdosage, treatment should be symptomatic and supportive. Proton Pump Inhibitors. AcipHex is for short-term use only, usually 4 to 8 weeks. Healthcare professionals sometimes prescribe Aciphex for off-label to treat functional dyspepsia, a condition that causes upset stomach and pain in the upper abdomen. The Aviphex profile of rabeprazole in the maintenance studies was consistent with what was observed in the acute studies. By using this site, you agree to the Terms of Use and Privacy Policy. See Contraindications. Monitor INR and prothrombin time. Use: Long-term treatment of pathological hypersecretory conditions e. Available for Android and iOS devices. Patients with persistent H.
Common use

Aciphex is an antiulcer medication which inhibits a proton pump (PPIs) and blocks the production of acid by the stomach. Biochemically it blocks the (H+,K+)-ATPase enzyme system hereby inhibiting the final stage of hydrochloric acid production. After peroral intake of Aciphex antisecretorial effect is reached during one hour and is maximal in 2-4 hours. This medication is used to treat ulcers in stomach, Zollinger-Ellison syndrome, gastroesophageal reflux disease, to eradicate Helicobacter pylori in patients with ulcers in stomach or chronic gastritis.



Dosage and directions

Dosage should be administered by your doctor depending on your condition. Usually in patients with an acute duodenal ulcer and c it is recommended to take 1 tab (20 mg) in morning one time a day during 4-6 weeks. When treating H. pylori infection, Aciphex may be needed for only a week. Follow all recommendations of your doctor and do not take this drug in larger amounts than it was prescribed to you. Tablets should be swallowed whole. Do not crush, split or chew them. Take Aciphex with or without meals with a big glass of water since food has little effect on its absorption.



Precautions

Notify your doctor if you have a severe liver disease, cancer of stomach before to take this drug. Use of Aciphex in children is not recommended. It is not expected to be harmful to an unborn baby, though inform your doctor if you are pregnant or breastfeeding. Some conditions are treated with a combination of Aciphex and antibiotics, so to achieve maximal effect from treatment, use all of your medications as directed by your doctor.



Contraindications

Pregnancy, breastfeeding, hypersensitivity to Aciphex or a substituted benzimidazoles: omeprazole (Prilosec, Zegerid), lansoprazole (Prevacid), pantoprazole (Protonix), rabeprazole (Aciphex), and esomeprazole (Nexium).



Possible side effect

Together with symptoms of allergy (hives, rash, swelling of tongue and face) such side effects may occur: headache, dizziness, dry mouth, upset stomach or diarrhea, constipation, insomnia, nervousness, rash, or itching. Contact your doctor for help if any of the listed side effects is severe or persistent.



Drug interaction

Co-administration with the medications which absorption depends on acidity of the stomach causes interaction of medications. Aciphex and other PPIs reduce the absorption and concentration in blood of ketoconazole (Nizoral) and increase the absorption and concentration in blood of digoxin (Lanoxin) causing reduction of effectiveness of the former and increase of toxicity of the latter.



Missed dose

If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule.



Overdose

Symptoms of Aciphex overdose are unknown. If you consider that you took too much of the drug seek emergency medical attention.



Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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