Epivir - with you Other possible side effects of combination therapy for HIV Combination therapy including Epivir may cause other conditions to develop during HIV treatment. What side effects can this medication cause. Study Description. Tell your doctor if you are pregnant, and use your medications properly to control your infection. Epivir mg film-coated tablets are supplied in white polyethylene bottles or blister packs containing 60 tablets. Avoid taking other medications that contain an ingredient called sorbitoloften used as a sweetener in liquid medicines. Long-term incidence of hepatitis B virus resistance to lamivudine in human immunodeficiency virus-infected patients. People may be more likely to get this condition:. Share Print. Lamivudine Epivir is usually taken once or twice a day with or without food. National Library of Medicine U. Continue Log out. The most common side effects caused by drug regimens containing Epivir are headache, diarrhea, and nausea. How should this medicine be used?. In studies, the most common side effects seen during treatment with EPIVIR-HBV were ear, nose, and throat infections; Epigir and fatigue feeling tired and run down ; headache; abdominal discomfort and pain; nausea and vomiting; diarrhea; muscle pain; sore throat; joint pain; fever or chills; and skin rash. Fatty lumps sometimes called buffalo hump may appear on the back of the neck. You have reached the HIVandHepatitis. You may need frequent liver function tests for several months. Search for terms x. A once-promising HIV vaccine trial was recently discontinued after it was found ineffective at preventing the virus. In initial therapy, many antiretroviral combinations containing lamivudine and a second nucleoside analogue plus an active agent from another class have been found to be effective at suppressing HIV viral load and increasing CD4 cell counts, and delaying clinical progression of HIV disease. Some medications proved more harmful than others. You have been inactive for 60 minutes and will be logged out in. Epivir contains a higher dose of lamivudine than Epivir-HBV. A retrospective analysis presented at CROI looked at risk of viral rebound in people who switched to lamivudine Epivir, 3TC -based dual antiretroviral therapy. As well as the side effects listed below for Epivirother conditions can develop during combination therapy for HIV. How Supplied: Tabs mg—60; mg—30; Soln—mL. Antiviral Therapy. Lamivudine is in a class of medications called nucleoside reverse transcriptase inhibitors NRTIs. Despite the presence of the signature lamivudine or emtricitabine resistance mutation, at reverse transcriptase codonlamivudine may have a suppressive effect on HIV replication and may increase susceptibility to certain other nucleoside analogues eg, tenofovir, zidovudine. You need to keep taking it every day to stop your illness getting worse. One mutation MV can reduce its effectiveness. Over time and after doing a lot of…. Dosage reduction is not necessary in hepatic impairment. DHHS Guidelines. Swallow the tablets, with some water. Take the container with you, even if it is empty. Why is this medication prescribed? Ask your pharmacist for a list of the ingredients. If the headaches continue, let your doctor know Feeling sick nausea or being sick vomitingtummy abdominal pain, wind, indigestion Stick to simple meals - avoid rich or spicy food. Read the information? You may need extra check-ups, including blood tests, while you? Tell your doctor or pharmacist if you? Any updates not saved will be lost. Study Type :. Researcher Charles W. Epivir does not completely cure HIV infection; it reduces the amount of virus in your body, and keeps it at a low level. David Hardy says: Epivir was approved in as the fourth antiretroviral medication and nuke. Your body shape may change People taking combination therapy for HIV may find Epivjr their body shape changes, because Epivkr changes in fat distribution: Fat may Eplvir lost from the legs, arms Epivkr face. In pediatric studies, lamivudine has been associated with pancreatitis; thus, combination with other medications associated with pancreatitis requires close monitoring in children. Antiviral activity of lamivudine in salvage therapy for multidrug-resistant HIV-1 infection. If you have any of the symptoms listed above, or any other symptoms that worry you: See your doctor as soon as possible. Children weighing 14? From Wikipedia, the free encyclopedia. You may still develop other infections and illnesses linked to HIV infection. Talk to your doctor if any of these apply to you. Uncoating inhibitors TRIM5alpha gene. Epivir was approved for the treatment of HIV by the U. All rights reserved. IUPAC name. Pediatric Dose: Age 3 month to 18 years: dosing based on body weight and should not exceed adult daily dose. Implications of resistance to other antiretrovirals for treatment with lamivudine. DHHS Guidelines. You may need frequent liver function tests for several months. If you have any unwanted Epivir tablets, don?
Epivir is an antiviral medication which used to fight infection with the human immunodeficiency virus (HIV), the deadly cause of AIDS. Epivir prevents the cells from producing new virus and decreases the amount of virus in the body. This drug is also prescribed for the treatment of chronic hepatitis B infection. Note that this medication must be used in combination with other HIV drugs.
Dosage and direction
Take it orally with or without food/milk at the same time each day. The Epivir dose normally used to treat hepatitis B for adults is one 100mg tablet once a day. The recommended dosage for treatment HIV is one 300mg tablet once daily or one 150mg tablet every 12 hours.
Children dosage depends on the weight of the child, and their ability to swallow pills. The liquid formulation should be given 4 mg per kilogram of body weight, up to a maximum of 150 milligrams twice daily.
Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.
Do not take it without doctor's permission if your medical history include: kidney disease; liver disease; pancreatitis; problems with your muscles; or problems with your blood counts. Remember that this drug does not reduce the risk of passing the HIV or hepatitis B virus to others. Do not use alcohol because it may increase the risk of damage to the pancreas and/or liver. Epivir should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use Epivir before breast-feeding without doctor's advice.
Epivir is not allowed in people who are hypersensitivity to the active substance or to any of the excipients.
Possible side effect
They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include:
liver damage, stomach pain, clay-colored stools, low fever, loss of appetite, dark urine, jaundice; muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, nausea with vomiting, and fast or uneven heart rate; pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate; peripheral neuropathy - numbness, tingling, or pain in your hands or feet; easy bruising or bleeding, unusual weakness, pale skin; white patches or sores inside your mouth or on your lips; fever, chills, body aches, flu symptoms; any other signs of new infection.
Less serious include:
cough; sleep problems (insomnia), strange dreams; nausea, vomiting, diarrhea; joint or muscle pain;
dizziness, headache, tired feeling; changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk).
If you experience one of them stop using Epivir and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.
Epivir interact with interferon-alfa (Roferon, Intron, Rebetron); trimethoprim (Bactrim, Proloprim, Septra, Trimpex); or ribavirin (Rebetol, Ribasphere, Copegus Virazole). Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.
If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.
Symptoms of Epivir overdose are not known. So if you experience any unusual symptom call your doctor immediately.
Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.