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Generic Glucophage (Metformin)
Glucophage is an oral diabetes medicine used to treat type 2 of diabetes.
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It is designed to assist doctors Glucophaage pharmacists in prescribing and supplying the product. Annual GGlucophage to the Nation. For women who are breastfeeding: This drug may pass into breast milk and may cause side effects in a child who is breastfed. For the active ingredient metformin. This link will take you to a website to which our Privacy Policy and Conditions may not apply. The British Journal of Radiology. Levels of Evidence: Treatment. Never try to catch up by taking two doses at once. Interest in metformin resumed at the end of the s. This can affect how your kidneys work and put you at risk of lactic acidosis. It can also be used to treat polycystic ovarian syndrome PCOS. Your doctor may Glucophage change your dose. Metformin accumulation occurs at acute worsening of renal function and increases the risk of lactic acidosis. Article 30 referrals. For each version, we show the dates it was published on medicines. Newsletter Signup. Archived from the original on 17 December From Wikipedia, the free encyclopedia. Medicinal products that can acutely impair renal function such as antihypertensives, diuretics and NSAIDs should be initiated with caution in metformin-treated patients. Symptoms include weakness, unusual muscle pain, trouble breathing, unusual sleepiness, and stomach pains. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizzinessfeeling cold, or feeling very weak or tired. Glucophage is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Active Ingredients cetuximab. Glucophage drug interactions in more detail. We're sorry, but we're unable to process your login. Subscribe to Drugs. A combination of metformin and rosiglitazone was released in and sold as Avandamet by GlaxoSmithKline. These chemical parameters indicate low lipophilicity and, consequently, rapid passive diffusion of metformin through cell membranes is unlikely.

Glucophage - that would

American Journal of Clinical Dermatology. The American Diabetes Association and the American College of Physicians each recommend metformin Gucophage a first-line agent to treat type 2 diabetes. Gludophage function. Acarbose Miglitol Voglibose. Insulin is a hormone that helps your body remove extra sugar from your blood. Glucophage mg: White, oval, biconvex film-coated tablets of dimensions 19 mm x The extended-release tablet is available as the brand-name drugs Glucophage XR, Fortamet, and Glumetza. Introduction to Grants Process. Burkina Faso Burkina Faso. Current Congress. Interest in metformin resumed at the end of the s. As a result of its low lipid solubility it requires the transporter SLC22A1 in order for it to enter cells. You need to eat or drink one of the following:. Garcia [] used metformin he named it Fluamine to treat influenza; he noted the medication "lowered the blood sugar to minimum physiological limit" and was not toxic. The metformin pK a values make it a stronger base than most other basic medications with less than 0. Our company is always the customer with the most reliable resources of manufacturer and generic drug suppliers in the world. Food and Drug Administration FDA announced that it learned that some metformin medicines manufactured outside the United States might contain a nitrosamine impurity called N-nitrosodimethylamine NDMAclassified as a probable human carcinogen, at low levels. If your blood sugar is still low, then repeat the above treatment. Metformin is generally safe in people with mild Gluclphage moderate chronic kidney disease, with proportional reduction of metformin dose according to severity of estimated glomerular filtration rate and with periodic assessment of kidney function, e. The tablet is embossed "GL" on the scored face. In other projects Wikimedia Commons. Metformin is a prescription drug used to treat type 2 diabetes.
Common use

Glucophage is an oral diabetes medicine used to treat type 2 of diabetes. Its active substance is Metformin which belongs to biguanide class of substances. It reduces concentration of glucose in blood suppressing metabolism of glucose in the liver, reducing absorption of glucose from the gastrointestinal tract, and enhancing its utilization in tissues. Glucophage stabilizes or reduces body weight. The therapeutic effect is not observed in the absence of insulin in the blood. It does not cause hypoglycemic reactions. It improves fibrinolytic properties of blood. It I used to treat diabetes mellitus (type 2) in adults also in patients for who treatment with sulfonylurea was ineffective, especially in cases followed by obesity.



Dosage and direction

Do not take if this medication was not prescribed to you and do not exceed the recommended dose. Take it with a meal if your doctor did not recommend you to take it differently. Glucophage is administered for taking twice daily by 500 mg or 850 mg once daily to treat type 2 diabetes in adults. Basing on the glucose levels in the blood the dose of Glucophage can be increased to the maximum daily dose of 2550 mg given in three divided doses.



Precautions

This medication is able to cause a life threatening condition in some people which is characterized by weakness, increasing sleepiness, slow heartbeat, cold feeling, muscle pain, abdominal pain, shortness of breath, feeling light-headed, and fainting. It is called lactic acidosis. If you experience such symptoms get immediate medical attention. Also be attentive to symptoms of low blood sugar which include hunger, confusion, irritability, drowsiness, headache, weakness, fast heartbeat, tremors, sweating, seizure and have a source of sugar at hand always. Avoid drinking alcohol.



Contraindications

Hypersensitivity, hyperglycemic coma, ketoacidosis, kidney failure, liver disease, heart failure, acute myocardial infarction, respiratory failure, dehydration, infectious diseases, extensive surgery and trauma, alcoholism, reduced-calorie diet (less than 1000 kcal / day), lactic acidosis (including history), pregnancy, breastfeeding. The drug is not prescribed to take 2 days before a surgery, radioisotope and X-ray examinations, CAT scanning (CT). Glucophage is contraindicated in patients over 60 y.o., or doing hard physical work (risk of lactic acidosis increases).



Side effects

The following side effects are most common and be rather severe to stop taking of the medication: swelling or rapid weight gain, nausea, vomiting, gas, bloating, diarrhea and loss of appetite. In case of lactic acidosis also get emergency medical help: weakness, increasing drowsiness, slow heartbeat, cold feeling, shortness of breath, abdominal pain, muscle pain, lightheadedness, and fainting. Allergic reaction is also possible: hives, swelling, rash.



Drug interaction

Cimetidine (Tagamet) increases blood levels of Glucophage affecting its metabolism. Glucophage is not compatible with alcohol. Concomitant administration with indirect anticoagulants and Cimetidine should be done with cautiousness. Glucophage enhances metabolism of Furosemide. Derivatives of sulfonylurea, insulin, acarbose, inhibitors of MAO, oxytetracycline, cyclophosphamide and salicylates increase the effects of Glucophage. Decrease of hypoglycemic effect of Glucophage is caused by co-administration with thyroid medicines, birth control pills and other hormones, Epinephrine, Glucagon, thiazide diuretics, nicotinic acid derivates.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or time for your next dose is in a short while. Do not take double doses of this medication or extra doses of it. Take your usually dose next day in the same regularly time.



Overdose

Symptoms of Glucophage overdose are ones of low blood sugar: hunger, confusion, irritability, drowsiness, headache, weakness,, tremors, sweating, fast heartbeat, seizure and have a source of sugar at hand always. If you experience one of them or any unusual symptoms call your doctor immediately.



Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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