Latest News. Due to the potential for serious Isoptin reactions in nursing infants, verapamil should only be used during lactation if it is essential for the welfare of the mother. Cardiac disorders. Reasons for updating New SmPC for new product. General disorders and administration site conditions. Infectious Diseases. Maculopapular rash. H2 Receptor antagonists. Last updated on Oct 3, Retrieved 14 November Neuropathy peripheral. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Erectile dysfunction Gynaecomastia Galactorrhoea. Therefore, it is not possible to estimate the true incidence of adverse events or establish a causal relationship to verapamil exposure. For this reason, when one wants to avoid taking valproic acid which is high in teratogenicity or lithium which has a small but significant incidence of causing cardiac malformationverapamil is usable as an alternative, albeit presumably a less effective one. A number of metabolites are generated in humans twelve have been identified. Think your supplement is safe? Hong Kong. There is a total of 5 error s on this form, details are below. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. August June Psychiatric disorders. Error: This is required. Isoptin SR tab mg. Seniors: Seniors may have a higher risk of side effects with this medication. Deletion of hypotension text. Terms and conditions of use. These are not all of the side effects that may occur. H2 Receptor antagonists. Verapamil may also reduce liver function and can cause liver failure. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. Myanmar Philippines Singapore Thailand Vietnam. Uncompensated heart failure to be treated by the physician before initiating treatment. If you have liver problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Be sure to keep an adequate supply on hand. Cardiac arrest. Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children. See Isopyin instead. Amiloride Benzamil Triamterene. Reasons for updating Improved electronic presentation. Tell your doctor about all your current medicines and any you start or stop using, especially:. Follow all directions on your prescription label. If you miss a dose, take it as soon as possible and continue with your regular schedule. Do not chew or crush the sustained-release tablets. Retrieved 17 May Error: Not a valid value. Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. Medically reviewed by Drugs.
Isoptin is a Ca2+-channel blocker which relaxes (widens) veins and arteries, which makes it easier for the heart to pump and this way Isoptin reduces its workload. Calcium triggers contraction of smooth muscles and when its entrance to the myocytes, it results in relaxation of the arterial muscles, improved oxygen delivery to the myocardial tissue, and decreased total peripheral resistance, systemic blood pressure, and after-load. Isoptin also decreases the conduction of electrical impulses through the heart that control the coordination of contraction, this slows the rate of contraction. Isoptin is used to treat hypertension, to treat angina, control some types of irregular heartbeats.
Dosage and direction
Take orally with or without food. Daily dose is 180-480 mg which may be taken as a single dose or divided in two or three intakes. Take exactly as prescribed by your doctor, never exceed the dose recommended to you.
Avoid drinking alcoholic beverages, grapefruit juice or eating grapefruit. Alcohol is able worsen side effects of Isoptin (drowsiness and dizziness) while grapefruit interacts with components of the drug. Do not get up too fast from a sitting or lying position as you may feel dizzy.
Isoptin is contraindicated in patients with hypersensitivity to components of the medication, severe left ventricular dysfunction, hypotension (systolic pressure less than 90 mm Hg) or cardiogenic shock, sick sinus syndrome (except in patients with a functioning artificial ventricular pacemaker), atrioventricular block degree II-III (except in patients with a functioning artificial ventricular pacemaker), atrial flutter or atrial fibrillation and an accessory bypass tract (Wolff-Parkinson-White, Lown-Ganong-Levine syndromes).
Arpamyl is usually well tolerated. Most common side effects include dizziness, weakness or fainting, swelling of the lower extremities, rash, headache, and constipation. Jaundice, swelling, difficulty breathing, rashes are also possible. If you experience severe side effects listed above seek for immediate medical attention.
Isoptin inhibits elimination of alcohol, increases the efficacy of doxorubicin both in tissue culture systems and in patients. Cyclophosphamide, oncovin, procarbazine, prednisone (COPP) and the vindesine, adriamycin, cisplatin (VAC) cytotoxic drug regimens are able to decrease absorption of Isoptin. Co-administration of Isoptin with aspiring in rare cases increases risk of bleeding. Correction of digoxin dosage is important in patients treated with Isoptin. Chronic verapamil treatment can increase serum digoxin levels by 50% to 75% during the first week of therapy leading to digitalis toxicity. Co-administration with oral antihypertensive agents results in additive effects. Inform your doctor about all medications you take, especially about Disopyramide, Flecainide, Quinidine, Phenobarbital, Cyclosporin, medications which contain lithium. This medication may change results of certain liver tests to mildly abnormal.
Take the dose you forgot as soon as you remember. If it is almost time for your next intake just skip the next dose and return to your regular schedule.
If you experience slow heartbeat and fainting, they may be symptoms of overdose. Seek for immediate medical attention if you suppose that too much of Isoptin was taken.
Store at room temperature 15-30 C (59-86 F) away from light, moisture, pets and children.
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