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Generic Rebetol (Ribavirin)
Rebetol is used in combination with interferon drugs Intron A or PEG-Intron to treat chronic hepatitis C.
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It is Rebftol known if using Rebetol in children younger than 3 years old Rebetil safe or if it will work. Available for Android and Revetol devices. See also: Rebetol side effects in more detail. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Ribavirin can harm Reberol unborn baby or cause birth defects if the mother or the father is using this medicine. Measure liquid medicine carefully. Anemia can cause severe fatigue, dizziness, headaches, and shortness of breath; routine blood testing for anemia, neutropenia, and other blood conditions is recommended. Road, Thane -Dist. The limited distribution of P-INFa-2a results in a longer half-life. In infants, children, and adults over the age of 65, pneumonia can be deadly. It previously played a major part in HCV treatment for years when used in combination with interferon but is not generally reserved for certain patient populations with severe hepatic impairment. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The severity of some of these systemic symptoms e. Pregnancy Testing REBETOL therapy should not be started until a report of a negative pregnancy test has been obtained immediately prior to planned initiation of treatment. Back Next. Difficulty breathing may be a sign of a serious lung infection pneumonia that can lead to death. The recommended duration of treatment is 48 weeks for pediatric patients with genotype 1. Refer to PegIntron labeling for PegIntron dosing information. Grant Closeout. Concomitant azathioprine; may induce severe pancytopenia and increase risk of myelotoxicity monitor CBCs. Legislative Resources. We will review and answer your question shortly. Combination treatment including Rebetol was effective in around a quarter of the Regetol whose disease had Rebetol back after previous treatment or whose previous treatment did not work, and over half of the children and adolescents treated. Retrieved 8 December The main measure of effectiveness in these studies was the Rebeetol of patients who had no detectable hepatitis C virus in their blood 24 weeks after the end of the treatment and could therefore be considered to be cured. IUPAC name. Email this page. For additional information on Rebetol capsules, Rebetron Combination Therapy and other company products, please visit Schering-Plough. Study Findings. Spotlight on Scientists. Latest Drug Information Updates. Screening Tests. Back Next. Stories of Discovery. What tips would you provide a friend before taking Rebetol? Depending upon the manufacturer, tablets are available in mg, mg, mg, and mg. Ribavirin is used primarily to treat hepatitis C and viral hemorrhagic fevers which is an orphan indication in most countries. Inform MD Back to Top. Previous NCI Directors. Unfortunately, most people who are infected with hepatitis C are unaware of it because it may take years for symptoms to develop.

Rebetol - like topic

It is given Rebetil either fixed doses or in doses related to weight weight-based. What benefit Rebetol Rebetol shown during the studies. In many but not all cases, adverse reactions resolved after dose reduction or discontinuation of therapy. In relapse subjects, the mean maximum decrease from baseline was 2. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Using Rebetol will not prevent you from passing hepatitis to other people. Skip to Content. Why has Rebetol been approved? The dose your doctor recommends may be based on the following: the condition being treated other medical conditions you have other medications you are taking how you respond to this medication your weight your height your age your gender Rebetol capsules and solution are typically given as mg mg per day in two divided doses. Patients with a history of significant or unstable cardiac disease should not be treated with Rebetol. Jump to: navigationsearch. Manufacturer Back to Top. CNT2 binds to the ribose of the ribavirin via hydrogen bonding involving glutamic acid at positionasparagine at positionand serine at position [5]. Use 2 forms of birth control to prevent pregnancy while either sexual partner is taking Rebetoland for at least 6 months after treatment ends. The limited distribution of P-INFa-2a results in a longer half-life. Swelling and irritation of your pancreas pancreatitis. Pharmacologic Class: Nucleoside analogue. Take this medication exactly as prescribed by your doctor. Manufacturer Rebetol solution: Merck; ribavirin tablets or capsules generic : Manufacturers vary. For a full list of restrictions, see the package leaflet. How has Rebetol been studied? See also: Rebetol drug interactions in more detail. Generic Back to Top. By the end of the 6-month follow-up period, the incidence of ongoing adverse reactions by body class in the PegIntron 1. Follow us on: Facebook Twitter linkedin. Be sure to have regular dental exams while you are taking this medication. Related Brands. Daily news summary. Antiviral Activity in Cell Culture The antiviral activity of ribavirin in the HCV replicon is not well understood and has not been defined because of the cellular toxicity of ribavirin. Rebetol is an oral formulation of ribavirin, a synthetic nucleoside analog with antiviral activity. In the U. Get medical help right away if you experience chest pain. Call your doctor at once if you have pale or yellowed skin, dark colored urine, fever, confusion, chest pain, weakness, or trouble breathing. Ribavirin solution liquid and generic tablets are also available. We will review and answer your question shortly. Genotype 1 2 3 4 5 6. There are no data on the presence of ribavirin in human milk or the effects on the breastfed infant or milk production. We use cookies to provide you with a better experience. In rare cases, ribavirin can cause fatal heart problems.
Common use

Main component of antiviral drug Rebetol is Ribavirin. It is used in combination with interferon drugs Intron A or PEG-Intron to treat chronic hepatitis C. Rebetol inhibits the replication of new virions, selectively inhibits synthesis of viral RNA, it does not suppress synthesis of RNA in a normal cells. Rebetol is the most effective against: herpes simplex virus, virus of smallpox, influenza viruses A and B, paramyxovirus (parainfluenza, mumps, Newcastle disease), reovirus, oncogenic RNA viruses.



Dosage and direction

Make sure you drink plenty of water while taking Rebetol, especially with your first intakes of the medication. Treatment continues for 24-48 weeks. To treat hepatitis C take Rebetol orally with food and full glass of water. Do not chew the tablet, swallow it whole. Recommended dose of Rebetol is 1-1.2 g a day divided in two for morning and evening intakes.



Precautions

Rebetol is may cause a significant risk of serious harm to developing infants and abnormalities in a man's sperm, be very attentive using contraception medications. At least two forms of birth control during treatment and for six months afterwards are required.



Contraindications

Rebetol is contraindicated in patients hypersensitive to the components of Rebetol, in pregnant and breastfeedign women, in patients with chronic heart failure, myocardial infarction, kidney or liver failure, severe anemia, decompensated cirrhosis, autoimmune diseases, incurable thyroid disease, severe depression with suicidal intentions, children and adolescents under 18. Cautiousness should be exercised in patients with decompensated diabetes mellitus, pulmonary embolism, heart failure, thyroid disease (including hyperthyroidism), impaired clotting, thrombophlebitis, myelosuppression, haemoglobinopathy (thalassemia, sickle cell anemia), depression, suicidality (also in history).



Possible side effect

The most serious adverse reaction to Rebetol is anemia. Other side effects include: blood disorders, fever, hair loss, depression, fatigue, headache, insomnia, irritability, nausea, shortness of breath, joint or muscle pain, weight loss. Notify your doctor immediately if you experience any serious manifestation of the side effects listed above.



Drug interaction

Concomitant use with other antiviral drugs such as zidovudine (Retrovir), zalcitabine (Hivid) or stavudine (Zerit), may cause lactic acidosis. Medications which contain Mg2+ Г‰ Al3+, and also simethicone decrease absorption of Retrovir. Retrovir suppresses effects of zidovudine. In the patients with HIV infection concomitant treatment with Retrovir, zidovudine and stavudine leads to HIV viremia (a condition where viruses get into the bloodstream and can affect the rest of the body) and requires change of treatment.



Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.



Overdose

If you suppose that took too much of this medication seek immediate medical attention. There is no information about adverse effects of Rebetol overdose.



Storage

Rebetol should be stored at room temperature between 2-8 C (36-46 F).



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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