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Generic Zocor (Simvastatin)
Zocor is a cholesterol- lowering medication prescribed to inhibit the production of cholesterol by the liver.
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Simvastatin 40 mg-TEV, pink, round. Can the medication cause this? Q: I have been on Zocor 40 mg for a few years. Store the tablets at room temperature and away from excess heat and moisture not in the bathroom. For more specific Zoco, consult with your doctor or pharmacist for recommendations based on your specific condition and current medications. Accumulation of cholesterol and fats Zocr the walls of your arteries a process known oZcor Zocor decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lori Poulin, PharmD. Although effective, there are some side effects and drug interactions you should watch out for when taking Zocor. Remember to always consult your physician or health care provider before starting, stopping, or altering a treatment or health care regimen. The benefits of the combined use of simvastatin with the following drugs should be carefully weighed against the potential risks of combinations: other lipid-lowering drugs fibrates or, for patients with HoFH, lomitapideamiodarone, dronedarone, verapamil, diltiazem, amlodipine, or ranolazine [see Dosage and Administration 2. The statin drugs like atorvastatin Lipitor and simvastatin Zocor are overwhelmingly the first choice. Outcome Measures. Epub Mar 4. Ezetimibe SCH Vitamin D is found in very few foods, unless added as fortification. Do not freeze or refrigerate the suspension. Because of Zocor's beneficial effects on cholesterol and other fatty substances in the blood, Zocor is used to reduce the risk of dying, by reducing heart disease deaths, in people at a high risk of having an adverse heart event. Childhood Cancer Genomics. If you would like to Zoco with a customer service representative, you can reach them at between the hours of ampm cst. Am J Cardiol. These drugs should not be used while you are taking Zocor:. This compares to Simvastatin side effects. Take Zocor exactly as prescribed. Erratum in: Pharmacol Ther May;86 2 A: To take Zocor simvastatinto lower cholesterol and reduce the risk for coronary heart disease and cardiovascular events, it is essential for patients to take Zocor exactly as directed by their health care provider. A: Zocor simvastatin is classified as a statin Zocor that lowers cholesterol production in the body. Questions to Ask about Your Diagnosis. Heat and dampness can destroy some medicines. Archived from the original on 28 September Studies show that it is usually well-tolerated and taken by many patients. These drugs should not be used with simvastatin. But if you have a cardiovascular condition — or are likely to develop one — and can't reach your LDL goals with a statin alone, it's a reasonable choice. The main benefits of generic Zocor include reduction of elevated cholesterol levels and reduction in the risk of coronary heart disease mortality and cardiovascular events. Patients receiving 80 mg per day should have another test 3 months after starting treatment with the 80 mg dose and periodically twice per year thereafter. Retrieved 22 December Q: I began taking Zocor about two years ago, and instantly started putting on pounds. Is that okay? The most common side effects associated with simvastatin are myalgia or muscle pain, headache, constipation, and nausea. Do not exceed 10 mg simvastatin daily with: Gemfibrozil Cyclosporine Danazol. Serious side effects are rare. A good time would be after your evening meal. The development of simvastatin was closely linked with lovastatin.

Congratulate, you: Zocor

VOLTAREN Calan Sr
Zocor This list is not complete and many other drugs can interact with simvastatin. One man shares how - and why - he learned to meditate even though he…. Pediatr Pathol Mol Med. Hepatic CYP3A4. Research has shown that the highest dose of simvastatin, 80 milligrams, causes muscle damage in 61 of every 1, patients, far higher than the eight-per, rate in patients taking a milligram dose, Rosenblatt says. Drug Class. Levels of Evidence: Cancer Genetics. Related Drugs. The U. The company assumes no duty to update the information to reflect subsequent developments. In this trial, which lasted 5. Hoboken, N. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Making a Difference. Triglycerides are an energy source for the body. See also: Zocor side effects in more detail. Cancer Causes and Prevention. USA Today. By using this site, you agree to the Terms of Use and Privacy Policy.
Ventolin pills This Zocoor may cause other side effects. Relative to the fasting state, the plasma profile of inhibitors was not affected when simvastatin was administered immediately before Zocorr American Zocpr Zocor recommended low-fat meal. The risk of myopathy, including rhabdomyolysis, is increased by concomitant administration of amiodarone, dronedarone, ranolazine, or calcium channel blockers such as verapamil, diltiazem, or amlodipine [see Dosage and Administration 2. Zocpr statin drugs like atorvastatin Lipitor and simvastatin Zocor are overwhelmingly the first choice. It is unknown if this risk applies to other Asian patients [see Warnings and Precautions 5. Inpublication of the results of the Scandinavian Simvastatin Survival Study 4S provided the first unequivocal evidence that lowering LDL cholesterol via statin treatment reduces cardiovascular events and overall mortality. Do not freeze or refrigerate the suspension. Drug Information available for: Simvastatin. National Library of Medicine. Questions to Ask about Advanced Cancer. The cholesterol-lowering drug simvastatin can cause severe muscle damage and should not be prescribed in high doses to patients who have taken it for less than a year or in any dose to people taking certain drugs, health officials said Tuesday. There are no adequate and well-controlled studies of use with ZOCOR during pregnancy; however, there are rare reports of congenital anomalies in infants exposed to statins in utero. Tablets ZOCOR for oral administration contain either 5 mg, 10 mg, 20 mg, 40 mg or 80 mg of simvastatin and the following inactive ingredients: ascorbic acid, citric acid, hydroxypropyl cellulose, hypromellose, iron oxides, lactose, magnesium stearate, microcrystalline cellulose, starch, talc, and titanium dioxide. Angiographic Studies In the Multicenter Anti-Atheroma Study, the effect of simvastatin on atherosclerosis was assessed by quantitative coronary angiography in hypercholesterolemic patients with CHD. Lipid determinations should be performed after 4 weeks of therapy and periodically thereafter. Atherosclerosis is a chronic process, and discontinuation of lipid-lowering drugs during pregnancy should have little impact on long-term outcomes of primary hypercholesterolemia therapy. There was no evidence of hypersensitivity. Change in plasma tissue factor TF levels after treatment with simvastatin. On or before November 1, These include itraconazole, ketoconazole, posaconazole, voriconazole, the macrolide antibiotics erythromycin and clarithromycin, and the ketolide antibiotic telithromycin, HIV protease inhibitors, boceprevir, telaprevir, the antidepressant nefazodone, cobicistat-containing products, or grapefruit juice [see Clinical Pharmacology.
Zocor I had Zocro B 30 years ago. The following drugs can Zocor your risk of serious muscle problems if you take them together with Zocor. A: It has ZZocor shown that soy, flaxseed oil, fish oil, green tea and garlic can all help to decrease cholesterol. Micromedex 2. The statin drugs like atorvastatin Lipitor and simvastatin Zocor are overwhelmingly the first choice. It is also important for patients to inform their health care provider of all other medications they currently take when considering treatment with Zocor.
Archived PDF from the original on 8 December However, as with cholesterol, too much Zicor can be a problem. Adult Treatment Editorial Board. Some may be better suited for you than others. Do not exceed 10 mg simvastatin daily with: Gemfibrozil Cyclosporine Danazol. You should always consult your doctor or other healthcare professional before taking any medication. In Allan Afuah ed. J Lab Clin Med. Data supporting the safety and tolerability of simvastatin in patients with SCD are now needed. Do not stop taking simvastatin without talking to your doctor. Actual Study Completion Date :. A search of prescribing information did not specifically list insomnia or frequent urination as side effects associated with Simvastatin. Gregory Latham, RPh. Q: What is the generic equivalent of Zocor? Patients receiving 80 mg per day should have another test 3 months after starting treatment with the 80 mg dose and periodically twice per year thereafter. Zocor categories: Webarchive template wayback links CS1 maint: unfit url CS1: long volume value Articles with short description Use dmy dates from October Template:drugs. It low-density lipoprotein LDL or "bad" cholesterol and total cholesterol, which can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease. Take the missed dose as soon as you remember. Take as directed. One of the most common adverse reactions associated with discontinuation of treatment during clinical studies was gastrointestinal disorders. This variant increases the plasma concentration of simvastatin, thus increasing the risk of myopathy. Your doctor may order certain lab tests during your treatment, especially if you develop symptoms of liver damage. Clinical Pharmacology and Therapeutics. Patients taking simvastatin 80 mg daily have an increased risk of myopathy compared to patients taking lower doses of this drug or other drugs in the same class. Adhesive interactions of sickle erythrocytes with endothelium. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient.
Common use

Zocor is a cholesterol-lowering medication which used to treat high cholesterol levels in the blood. It works by blocking the production of cholesterol in the body, thus can help prevent conditions that can lead to heart attack, heart disease and hardening of the arteries, stroke, and vascular disease. This medication can also reduce these risks in people with diabetes, peripheral vascular disease, and a history of stroke. Use this medication during low fat diet to get the best result.



Dosage and direction

Take this medication orally with or without food/milk.

The recommended starting dose of Zocor for adults is 20 to 40 milligrams once a day in the evening. The dosage can be varied every 4 weeks.

The recommended starting dose for children 10 to 17 years old is 10 milligrams once a day in the evening. The dosage can be varied every 4 weeks, but should not exceed 40 mg a day. Girls must have been menstruate for at least 12 months before starting therapy with Zocor.

Children under 10 years old only after doctor permission.

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.



Precautions

Before taking Zocor consult with your doctor if your medical history include: history of alcoholism, liver disease, severe infection, kidney disease, low thyroid function, heart disease, allergies. Try to limit alcohol intake because it can increase side effects. Also note: Zocor may increase your risk for liver problems. During the treatment with Zocor you may to limit the amount of grapefruit or grapefruit juice you may eat or drink (less than 1 quart a day) , because grapefruit juice may increase your risk for serious side effects.

For woman: Zocor should not be used during pregnancy, becoming pregnancy or lactating. Do not use before breast-feeding without doctor's permission.



Contraindications

Zocor is not allowed in patients with active liver disease or unexplained persistent elevations of serum transaminases or who are hypersensitivity to any component of this medication. Pregnancy and lactation. Atherosclerosis is a chronic process and the discontinuation of lipid-lowering medications during pregnancy should have little impact on the outcome of long-term therapy of primary hypercholesterolemia. Ability of inhibitors of HMG-CoA reductase such as Zocor can decrease the synthesis of cholesterol and possibly other products of the cholesterol biosynthesis pathway, so Zocor is contraindicated during pregnancy and in nursing mothers. Zocor should be administered to women of childbearing age only when such women are highly unlikely to become pregnant. If the patient conceve while taking this drug, Zocor should be discontinued immediately and the patient should be apprised of the potential hazard to the fetus



Possible side effect

They may include all types of an allergic reaction. Also the most possible side effects include:

muscle pain, tenderness, or weakness with fever or flu symptoms and dark colored urine.

Less serious include:

mild stomach pain, gas, bloating, stomach upset, heartburn;

nausea;

constipation; or

diarrhea.

If you experience one of them stop using Serevent and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.



Drug interaction

Zocor interact with such types of drugs as: danazol; gemfibrozil (Lopid), clofibrate, or fenofibrate;

niacin; nefazodone; cholestyramine or colestipol; warfarin; amiodarone, diltiazem, or verapamil;

erythromycin, clarithromycin, or telithromycin; an antifungal medication such as itraconazole, fluconazole, or ketoconazole; drugs that weaken your immune system such as cancer medicine or steroids, cyclosporine, sirolimus, tacrolimus, and others; HIV or AIDS medication such as amprenavir, indinavir, nelfinavir, ritonavir, lopinavir-ritonavir, or saquinavir. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.



Overdose

Overdose of Zocor is not danger for you life and iclude such symptoms: myalgia and red urine (in a severe overdose). If you experience one of them call your doctor immediately.



Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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